Systematic evaluation of 99mTc-tetrofosmin versus 99mTc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT
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منابع مشابه
Systematic evaluation of 99mTc-tetrofosmin versus 99mTc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT
BACKGROUND The "back-translation" of clinically available protocols to measure myocardial perfusion to preclinical imaging in mouse models of human disease is attractive for basic biomedical research. With respect to single-photon emission computed tomography (SPECT) approaches, clinical myocardial perfusion imaging protocols are established with different 99mTc-labeled perfusion tracers; howev...
متن کاملFilter selection for 99mTc-Sestamibi myocardial perfusion SPECT imaging [Persian]
Myocardial perfusion SPECT imaging with Tc99m-sestamibi is the most accurate non-invasive means of detecting coronary artery disease and assessing the severity of perfusion abnormalities in the patients with coronary stenosis. Though simple and straight forward the results produced by the technique is very much affected by the details being used. One of the main problems with the test, wh...
متن کاملReverse perfusion pattern in myocardial spect with 99mTc-SestaMIBI
RATIONALE The aim of our study was to investigate the myocardial perfusion deficit in rest images as compared to stress images in myocardial scintigraphy (MS). OBJECTIVES The aim of this study is to investigate the reverse perfusion (RP) pattern in MS. METHODS AND RESULTS 263 patients were enrolled in the study (72 females and 191 males; mean age 65.7 ± 9.5 years old). Mean body mass index ...
متن کاملImproving 99mTc-tetrofosmin Myocardial Perfusion Images by Time Subtraction Technique
Quantitative measurement of myocardium perfusion is possible with single photon emission computed tomography (SPECT) using a semiconductor detector. However, accumulation of 99mTc-tetrofosmin in the liver may make it difficult to assess that accurately in the inferior myocardium. Our idea is to reduce the high accumulation in the liver by using dynamic SPECT imaging and a technique called time ...
متن کامل99mTc-N-DBODC5, a new myocardial perfusion imaging agent with rapid liver clearance: comparison with 99mTc-sestamibi and 99mTc-tetrofosmin in rats.
UNLABELLED (99m)Tc-[bis (dimethoxypropylphosphinoethyl)-ethoxyethylamine (PNP5)]-[bis (N-ethoxyethyl)-dithiocarbamato (DBODC)] nitride (N-PNP5-DBODC or N-DBODC5) is a new monocationic myocardial perfusion tracer. We sought to compare the myocardial uptake and clearance kinetics and organ biodistribution of (99m)Tc-N-DBODC5 with (99m)Tc-sestamibi and (99m)Tc-tetrofosmin. METHODS Seventy-five a...
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ژورنال
عنوان ژورنال: EJNMMI Research
سال: 2012
ISSN: 2191-219X
DOI: 10.1186/2191-219x-2-21